skip to main content

HIV PrEP — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateAmbulatory Medicine / Primary CareHIV PrEPUSMLE Step 3

A 28-year-old man requests HIV prevention. He has condomless sex with male partners and had rectal gonorrhea 4 months ago. HIV antigen-antibody test is negative, creatinine is normal, and hepatitis B surface antigen is negative. He is willing to take daily medication. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Start HIV preexposure prophylaxis after baseline testing

Persons at increased risk of HIV acquisition should be offered effective PrEP after confirming negative HIV status and assessing renal and hepatitis B status.

Reference: USPSTF HIV Preexposure Prophylaxis Recommendation, 2023