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Overactive bladder — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareOveractive bladderUSMLE Step 3

A 62-year-old woman has urinary urgency and frequency with occasional urge leakage. Urinalysis and pelvic examination are normal, and postvoid residual is minimal. She has tried bladder training and fluid timing for 3 months without sufficient improvement. She has narrow-angle glaucoma controlled after laser iridotomy. Which of the following is the most appropriate next step in management?

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Correct answer: BStart mirabegron

Persistent overactive bladder after behavioral therapy can be treated with beta-3 agonists or antimuscarinics; mirabegron avoids anticholinergic burden.

Reference: AUA/SUFU Overactive Bladder Guideline