skip to main content

Osteoarthritis knee — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

EasyAmbulatory Medicine / Primary CareOsteoarthritis kneeUSMLE Step 3

A 64-year-old woman has gradual right knee pain for 2 years, worse with stairs and improved by rest. Examination shows bony enlargement, crepitus, and no warmth or large effusion. Radiograph shows medial joint-space narrowing and osteophytes. BMI is 34 kg/m2. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Recommend exercise, weight loss, and topical NSAID therapy

First-line knee osteoarthritis management includes exercise, weight loss when appropriate, and topical NSAIDs before invasive treatments.

Reference: ACR/Arthritis Foundation Osteoarthritis Guideline