A 27-year-old woman with SLE has new edema and hypertension. Urinalysis shows dysmorphic red blood cells and cellular casts. Urine protein-creatinine

Question

A 27-year-old woman with SLE has new edema and hypertension. Urinalysis shows dysmorphic red blood cells and cellular casts. Urine protein-creatinine ratio is 1.8 g/g and creatinine has increased from 0.7 to 1.2 mg/dL. Which of the following is the most appropriate next step in management?

Accepted Answer

Arrange kidney biopsy

Answer

Treat with antibiotics

Answer

Observe for 2 years

Answer

Stop hydroxychloroquine permanently

Answer

Increase sunscreen use alone

Lupus nephritis — USMLE Step 3 MCQ

A 27-year-old woman with SLE has new edema and hypertension. Urinalysis shows dysmorphic red blood cells and cellular casts. Urine protein-creatinine ratio is 1.8 g/g and creatinine has increased from 0.7 to 1.2 mg/dL. Which of the following is the most appropriate next step in management?