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Ascites in cirrhosis — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Ascites in cirrhosisUSMLE Step 3

A 62-year-old man with alcohol-related cirrhosis has new abdominal distention. Ultrasound shows moderate ascites and no portal vein thrombosis. He is afebrile and has no abdominal pain. Creatinine is 0.9 mg/dL. Which of the following is the most appropriate next step in management?

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Correct answer: DPerform diagnostic paracentesis

New ascites in cirrhosis requires diagnostic paracentesis to confirm portal hypertension and exclude spontaneous bacterial peritonitis.

Reference: AASLD Ascites Guidance