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Hepatitis C screening — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareHepatitis C screeningUSMLE Step 3

A 29-year-old man comes for a new-patient visit. He has no history of injection drug use, transfusion, or liver disease. He drinks 2 beers weekly. Alanine aminotransferase is normal. He asks whether hepatitis C testing is necessary despite lack of risk factors. Which of the following is the most appropriate screening recommendation?

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Correct answer: B — Screen once for hepatitis C antibody with reflex RNA testing

USPSTF recommends one-time hepatitis C screening for adults aged 18 to 79 years, with repeat testing for ongoing risk.

Reference: USPSTF Hepatitis C Virus Infection Screening, 2020