A randomized trial compares two diabetes medications. Ten percent of participants stop the assigned drug because of adverse effects. Investigators

Question

A randomized trial compares two diabetes medications. Ten percent of participants stop the assigned drug because of adverse effects. Investigators analyze participants in their originally assigned groups. Which of the following is the most likely explanation for this patient's findings?

Accepted Answer

Preservation of the benefits of randomization

Answer

Increasing measured adherence

Answer

Preventing loss to follow-up

Answer

Elimination of confounding by indication in observational data

Answer

Guaranteeing larger treatment effect

Intention-to-treat analysis — USMLE Step 3 MCQ

A randomized trial compares two diabetes medications. Ten percent of participants stop the assigned drug because of adverse effects. Investigators analyze participants in their originally assigned groups. Which of the following is the most likely explanation for this patient's findings?