A 31-year-old man is found unresponsive with respiratory rate 6/min and pinpoint pupils. Oxygen saturation is 82%. Friends report heroin use. He

Question

A 31-year-old man is found unresponsive with respiratory rate 6/min and pinpoint pupils. Oxygen saturation is 82%. Friends report heroin use. He improves after naloxone. Which of the following is the most likely explanation for this patient's findings?

Accepted Answer

Mu-opioid receptor agonism causing respiratory depression

Answer

Dopamine receptor blockade

Answer

Serotonin excess

Answer

Acetylcholinesterase inhibition

Answer

Sodium channel blockade

Opioid overdose — USMLE Step 3 MCQ

A 31-year-old man is found unresponsive with respiratory rate 6/min and pinpoint pupils. Oxygen saturation is 82%. Friends report heroin use. He improves after naloxone. Which of the following is the most likely explanation for this patient's findings?