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Septic shock reassessment — USMLE Step 3 MCQ

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ModerateEmergency MedicineSeptic shock reassessmentUSMLE Step 3

A 72-year-old man with pneumonia receives 30 mL/kg crystalloid and broad-spectrum antibiotics. Blood pressure remains 78/44 mm Hg and lactate is 4.8 mmol/L. He has no pulmonary edema. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DStart norepinephrine

Persistent hypotension after fluid resuscitation in septic shock requires vasopressor support, with norepinephrine first-line.

Reference: Surviving Sepsis Campaign guidelines