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Tobacco withdrawal — USMLE Step 3 MCQ

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ModeratePsychiatry (outpatient management)Tobacco withdrawalUSMLE Step 3

A 52-year-old man quits smoking abruptly. Three days later he has irritability, anxiety, difficulty concentrating, increased appetite, and cravings. Vitals and exam are normal. Which of the following is the most likely explanation for this patient's findings?

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Correct answer: ENicotine withdrawal

Irritability, anxiety, concentration difficulty, appetite increase, and craving soon after smoking cessation are typical nicotine withdrawal symptoms.

Reference: DSM-5-TR substance-related disorders