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Antidepressant adverse effect — USMLE Step 3 MCQ

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ModeratePsychiatry (outpatient management)Antidepressant adverse effectUSMLE Step 3

A 31-year-old woman started sertraline 3 weeks ago. Her mood is slightly improved, but she reports delayed orgasm and reduced libido. She takes no other medications. Which of the following is the most likely explanation for this patient's findings?

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Reveal the answer and explanation

Correct answer: E — SSRI-associated sexual dysfunction

Sexual dysfunction is a common SSRI adverse effect and should be discussed proactively.

Reference: APA practice guidance for depressive, anxiety, bipolar, and substance-use disorders