Croup — USMLE Step 3 MCQ
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Correct answer: A — Artemether-lumefantrine 4 tablets now and in 8 hours, then BID for 2 days
The best answer is “Artemether-lumefantrine 4 tablets now and in 8 hours, then BID for 2 days”. Ghana is a chloroquine-resistant setting and the six-dose artemether-lumefantrine schedule is preferred. For uncomplicated chloroquine-resistant falciparum malaria, preferred artemether-lumefantrine adult dosing is four tablets initially, four 8 hours later, then four twice daily on days 2 and 3. The alternatives use a different threshold, timing, population, or intervention and therefore do not match the clinical facts presented.
Reference: CDC: Malaria Treatment Tables: https://www.cdc.gov/malaria/hcp/clinical-guidance/malaria-treatment-tables.html