skip to main content

Rh alloimmunization prevention — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateOB/GYN (prenatal care, contraception, screening)Rh alloimmunization preventionUSMLE Step 3

A 28-year-old Rh-negative pregnant patient at 28 weeks' gestation has a negative antibody screen. The father is Rh-positive. There has been no bleeding. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Administer Rh(D) immune globulin

Explanation lettering: C = shown as A · A = shown as C · E = shown as D · D = shown as E

Unsensitized Rh-negative pregnant patients receive antenatal Rh(D) immune globulin at around 28 weeks and after sensitizing events or Rh-positive delivery.

Reference: ACOG prevention of Rh D alloimmunization guidance