skip to main content

Necrotizing soft tissue infection — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateSurgery (post-operative, follow-up)Necrotizing soft tissue infectionUSMLE Step 3

A 54-year-old man with diabetes has severe leg pain, fever, erythema, bullae, crepitus, and hypotension. Pain is out of proportion to skin findings. Creatinine is elevated. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BImmediate surgical exploration and debridement with broad-spectrum antibiotics

Necrotizing soft tissue infection requires urgent debridement plus broad-spectrum antimicrobial therapy.

Reference: IDSA skin and soft tissue infection guideline