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Mild cognitive impairment follow-up — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Mild cognitive impairment follow-upUSMLE Step 3

A 69-year-old man has mild cognitive impairment on testing but remains independent in activities of daily living. Medication review shows nightly diphenhydramine use for sleep. Which of the following would you recommend at the follow-up visit?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Stop anticholinergic medication and monitor cognition

Medication contributors such as anticholinergics should be addressed in cognitive impairment before escalating therapy.

Reference: American Academy of Neurology mild cognitive impairment guidance