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Diabetic ketoacidosis transition — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Diabetic ketoacidosis transitionUSMLE Step 3

A 28-year-old woman with diabetic ketoacidosis has improved after IV fluids and insulin. Anion gap is closed, bicarbonate is 20 mEq/L, she can eat, and potassium is 4.2 mEq/L. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: AGive subcutaneous basal insulin before stopping IV insulin

Basal insulin should overlap with discontinuation of IV insulin to prevent rebound ketosis.

Reference: American Diabetes Association Standards of Care in Diabetes—2026