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Graves disease treatment — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Graves disease treatmentUSMLE Step 3

A 35-year-old woman with Graves disease wants treatment. She is not pregnant, has mild ophthalmopathy, and prefers a noninvasive option. Liver enzymes and neutrophil count are normal. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AStart methimazole after counselling about adverse effects

Methimazole is generally preferred antithyroid drug therapy outside the first trimester and thyroid storm, with counselling about agranulocytosis and hepatotoxicity.

Reference: American Thyroid Association hyperthyroidism guideline