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Sickle cell disease health maintenance — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Sickle cell disease health maintenanceUSMLE Step 3

A 24-year-old man with sickle cell disease has three vaso-occlusive pain episodes requiring urgent care in the past year. He takes folic acid and has no chronic transfusion program. Which of the following would you recommend at the follow-up visit?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Discuss hydroxyurea therapy

Hydroxyurea reduces vaso-occlusive episodes in sickle cell disease and should be offered to eligible patients.

Reference: ASH sickle cell disease management guidance