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Inflammatory bowel disease flare — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Inflammatory bowel disease flareUSMLE Step 3

A 25-year-old man has chronic bloody diarrhea, urgency, and left lower-quadrant cramping. Colonoscopy shows continuous inflammation from the rectum to the sigmoid colon. Biopsy shows crypt abscesses. Which of the following is the most likely diagnosis?

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Correct answer: AUlcerative colitis

Continuous mucosal inflammation beginning at the rectum with crypt abscesses is characteristic of ulcerative colitis.

Reference: American College of Gastroenterology ulcerative colitis guideline