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Cirrhosis ascites — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Cirrhosis ascitesUSMLE Step 3

A 57-year-old man with alcohol-related cirrhosis has new moderate ascites. Diagnostic paracentesis shows no spontaneous bacterial peritonitis. Creatinine is normal and sodium is 136 mEq/L. Which of the following is the most appropriate next step in management?

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Correct answer: EStart sodium restriction plus spironolactone and furosemide

Uncomplicated cirrhotic ascites is managed with sodium restriction and diuretics, commonly spironolactone with furosemide.

Reference: AASLD cirrhosis ascites guidance