skip to main content

Heart failure preserved ejection fraction — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateInternal Medicine (chronic management)Heart failure preserved ejection fractionUSMLE Step 3

A 74-year-old woman with heart failure, ejection fraction 58%, hypertension, and diabetes returns after a mild fluid overload episode. She is now euvolemic. eGFR is 64 mL/min/1.73 m2. Which of the following would you recommend at the follow-up visit?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: EStart an SGLT2 inhibitor

SGLT2 inhibitors reduce heart failure hospitalizations in heart failure with preserved ejection fraction and are useful in diabetes.

Reference: 2022 AHA/ACC/HFSA Heart Failure Guideline