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Skin cancer triage — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareSkin cancer triageUSMLE Step 3

A 54-year-old man has a new asymmetric pigmented lesion with irregular borders and color variation on his upper back. It is 8 mm and has enlarged over 4 months. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Perform excisional biopsy with narrow margins

A changing lesion with ABCDE features concerning for melanoma requires diagnostic excisional biopsy when feasible.

Reference: American Academy of Dermatology melanoma guidance