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Chronic hepatitis C — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareChronic hepatitis CUSMLE Step 3

A 38-year-old man screened because of prior injection drug use has positive hepatitis C antibody and detectable HCV RNA. AST and ALT are mildly elevated. HIV test is negative. Which of the following is the most appropriate next step in management?

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Correct answer: ARefer for direct-acting antiviral treatment evaluation

Detectable HCV RNA confirms active infection; direct-acting antiviral therapy is recommended for most patients.

Reference: AASLD-IDSA hepatitis C guidance