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Chlamydia infection — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareChlamydia infectionUSMLE Step 3

A 22-year-old nonpregnant woman has dysuria and postcoital spotting. Nucleic acid amplification testing is positive for Chlamydia trachomatis and negative for gonorrhea. She has no pelvic pain or fever. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BTreat with doxycycline and arrange partner treatment

Uncomplicated chlamydia is treated with doxycycline in nonpregnant adults; partner management reduces reinfection.

Reference: CDC Sexually Transmitted Infections Treatment Guidelines; CDC doxycycline postexposure prophylaxis guidance