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COPD exacerbation outpatient — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareCOPD exacerbation outpatientUSMLE Step 3

A 68-year-old man with COPD has 3 days of increased dyspnea, sputum volume, and sputum purulence. Oxygen saturation is 94% on room air. He has no confusion or chest pain. Which of the following is the most appropriate next step in management?

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Correct answer: D — Short course of prednisone plus antibiotics

Increased dyspnea, sputum volume, and purulence support outpatient treatment for COPD exacerbation with bronchodilators, systemic steroids, and antibiotics when indicated.

Reference: ATS/ERS pulmonary guidance and GOLD COPD reports