skip to main content

Anaphylaxis — USMLE Step 2 CK MCQ

Instant feedback + full explanation. One question, done properly.

EasyEmergency MedicineAnaphylaxisUSMLE Step 2 CK

A 41-year-old Middle Eastern man comes to the clinic because of progressive symptoms. History and focused examination are notable for hypotension, wheezing, urticaria, and lip swelling after peanut exposure. Temperature is 101.5°F (38.6°C), blood pressure is 82/48 mmHg, pulse is 132/min, respirations are 28/min, and oxygen saturation is 90% on room air. Physical examination confirms the key finding and shows no unrelated abnormality that would better explain the presentation. Focused laboratory studies and initial testing support the clinical pattern described in the stem. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Intramuscular epinephrine

The vignette describes Anaphylaxis, supported by hypotension, wheezing, urticaria, and lip swelling after peanut exposure. Intramuscular epinephrine is the single best answer because it matches the diagnostic or management priority in this clinical setting. The other choices are plausible alternatives in related presentations, but they do not best fit the timing, findings, and guideline-directed approach described here.

Reference: NIAID Food Allergy and Anaphylaxis Guidelines