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Menopause vasomotor symptoms — USMLE Step 2 CK MCQ

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EasyObstetrics & GynecologyMenopause vasomotor symptomsUSMLE Step 2 CK

A 65-year-old Asian American woman comes to the emergency department because of pelvic symptoms or pregnancy-related concerns. History and focused examination are notable for hot flashes, night sweats, amenorrhea, and bothersome sleep disturbance. Temperature is 98.6°F (37.0°C), blood pressure is 126/78 mmHg, pulse is 84/min, respirations are 16/min, and oxygen saturation is 98% on room air. Physical examination confirms the key finding and shows no unrelated abnormality that would better explain the presentation. Focused laboratory studies and initial testing support the clinical pattern described in the stem. Which of the following is the most likely diagnosis?

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Correct answer: E — Menopause vasomotor symptoms

The vignette describes Menopause vasomotor symptoms, supported by hot flashes, night sweats, amenorrhea, and bothersome sleep disturbance. Menopause vasomotor symptoms is the single best answer because it matches the diagnostic or management priority in this clinical setting. The other choices are plausible alternatives in related presentations, but they do not best fit the timing, findings, and guideline-directed approach described here.

Reference: North American Menopause Society 2022 Hormone Therapy Statement