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Polycystic ovary syndrome — USMLE Step 2 CK MCQ

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EasyObstetrics & GynecologyPolycystic ovary syndromeUSMLE Step 2 CK

A 29-year-old White woman comes to the hospital because of pelvic symptoms or pregnancy-related concerns. History and focused examination are notable for oligomenorrhea, acne, hirsutism, obesity, and elevated free testosterone. Temperature is 98.6°F (37.0°C), blood pressure is 126/78 mmHg, pulse is 84/min, respirations are 16/min, and oxygen saturation is 98% on room air. Physical examination confirms the key finding and shows no unrelated abnormality that would better explain the presentation. Focused laboratory studies and initial testing support the clinical pattern described in the stem. Which of the following is the most likely diagnosis?

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Correct answer: A — Polycystic ovary syndrome

The vignette describes Polycystic ovary syndrome, supported by oligomenorrhea, acne, hirsutism, obesity, and elevated free testosterone. Polycystic ovary syndrome is the single best answer because it matches the diagnostic or management priority in this clinical setting. The other choices are plausible alternatives in related presentations, but they do not best fit the timing, findings, and guideline-directed approach described here.

Reference: Endocrine Society PCOS Guideline