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Mastitis — USMLE Step 2 CK MCQ

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ModerateObstetrics & GynecologyMastitisUSMLE Step 2 CK

A 26-year-old Native American woman comes to the clinic because of pelvic symptoms or pregnancy-related concerns. History and focused examination are notable for breast pain, fever, erythema, and focal tenderness during lactation. Temperature is 102.2°F (39.0°C), blood pressure is 108/66 mmHg, pulse is 112/min, respirations are 22/min, and oxygen saturation is 94% on room air. Physical examination confirms the key finding and shows no unrelated abnormality that would better explain the presentation. Focused laboratory studies and initial testing support the clinical pattern described in the stem. Which of the following is the most likely diagnosis?

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Correct answer: D — Mastitis

The vignette describes Mastitis, supported by breast pain, fever, erythema, and focal tenderness during lactation. Mastitis is the single best answer because it matches the diagnostic or management priority in this clinical setting. The other choices are plausible alternatives in related presentations, but they do not best fit the timing, findings, and guideline-directed approach described here.

Reference: https://www.ncbi.nlm.nih.gov/books/#stage-9-order-92