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Abnormal uterine bleeding — USMLE Step 3 MCQ

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ModerateOB/GYN (prenatal care, contraception, screening)Abnormal uterine bleedingUSMLE Step 3

A 47-year-old woman has heavy irregular uterine bleeding for 5 months. Pregnancy test is negative. BMI is 34 kg/m2. Pelvic examination shows no cervical lesion. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BPerform endometrial biopsy

Abnormal uterine bleeding at age 45 years or older requires endometrial sampling to evaluate hyperplasia or malignancy.

Reference: ACOG Abnormal Uterine Bleeding Guidance