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Post-traumatic stress disorder — USMLE Step 3 MCQ

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HardPsychiatry (outpatient management)Post-traumatic stress disorderUSMLE Step 3

A 10-week pregnant patient uses fentanyl daily and has moderate withdrawal after her last use. She wants a brief inpatient detoxification so that the fetus is no longer exposed to medication. Which recommendation is most appropriate?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AOffer methadone or buprenorphine maintenance with prenatal and addiction care

The best answer is “Offer methadone or buprenorphine maintenance with prenatal and addiction care”. Agonist treatment stabilizes maternal opioid exposure and reduces relapse, overdose, infection and inconsistent prenatal care. Medically supervised withdrawal has a high relapse rate and is not preferred; naloxone-precipitated withdrawal is dangerous.

Reference: ACOG Committee Opinion: Opioid Use and Opioid Use Disorder in Pregnancy: https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2017/08/opioid-use-and-opioid-use-disorder-in-pregnancy