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Surgical site infection — USMLE Step 3 MCQ

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ModerateSurgery (post-operative, follow-up)Surgical site infectionUSMLE Step 3

A 56-year-old man has fever and increasing pain 6 days after colectomy. The incision is erythematous with purulent drainage between staples. Blood pressure is normal and there is no peritonitis. Which of the following is the most appropriate next step in management?

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Correct answer: D — Open the incision and drain the wound

Purulent superficial surgical site infection requires opening the incision for drainage, with antibiotics added when systemic or deeper infection is present.

Reference: CDC Surgical Site Infection Guidance; IDSA Skin and Soft Tissue Infection Guideline