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Sepsis — USMLE Step 3 MCQ

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EasyEmergency MedicineSepsisUSMLE Step 3

A 72-year-old woman has fever, confusion, dysuria, blood pressure 84/48 mm Hg, lactate 4.2 mmol/L, and leukocytosis. Urinalysis suggests infection. Oxygen saturation is 96%. Which of the following is the most appropriate next step in management?

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Correct answer: EGive IV crystalloid and broad-spectrum antibiotics promptly

Sepsis with hypotension and elevated lactate requires prompt fluids, cultures when feasible, and broad-spectrum antibiotics.

Reference: Surviving Sepsis Campaign Guidelines