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Long-term oxygen therapy — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Long-term oxygen therapyUSMLE Step 3

A 70-year-old woman with severe COPD is clinically stable. Arterial blood gas on room air shows PaO2 54 mm Hg, repeated after optimisation of inhalers. She does not smoke. Which of the following would you recommend at the follow-up visit?

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Correct answer: APrescribe long-term oxygen therapy

Long-term oxygen improves survival in COPD with severe chronic resting hypoxemia.

Reference: GOLD COPD Strategy 2025