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Fragility fracture osteoporosis — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Fragility fracture osteoporosisUSMLE Step 3

A 71-year-old woman sustained a low-trauma distal radius fracture after a fall from standing height. DXA shows T-score -2.7 at the femoral neck. Creatinine clearance is 68 mL/min. Which of the following would you recommend at the follow-up visit?

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Correct answer: CStart oral bisphosphonate therapy

A fragility fracture with osteoporosis-range T-score warrants pharmacologic fracture-prevention therapy; bisphosphonates are common first-line agents.

Reference: Endocrine Society Osteoporosis Guideline