Generalized anxiety disorder — USMLE Step 3 MCQ
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Correct answer: E — Omit repeat maternal vaccine and give infant nirsevimab after birth
The best answer is “Omit repeat maternal vaccine and give infant nirsevimab after birth”. Current CDC guidance does not recommend repeat maternal vaccination in a later pregnancy; the infant should receive nirsevimab. In most of the continental US, maternal Abrysvo is given once at 32 0/7 through 36 6/7 weeks during September through January; after 36 6/7 weeks, protect the infant with nirsevimab instead. The alternatives use a different threshold, timing, population, or intervention and therefore do not match the clinical facts presented.
Reference: CDC: RSV Vaccine Guidance for Pregnant Women: https://www.cdc.gov/rsv/hcp/vaccine-clinical-guidance/pregnant-people.html