skip to main content

Hypertension — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateAmbulatory Medicine / Primary CareHypertensionUSMLE Step 3

A 61-year-old woman returns after 1 month of lifestyle changes for hypertension. Her home blood pressure log averages 151/88 mm Hg. She has no diabetes, chronic kidney disease, or cardiovascular disease. Serum creatinine and potassium are normal. Which of the following would you recommend at the follow-up visit?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: AStart chlorthalidone

Persistent stage 2-range hypertension generally warrants pharmacologic therapy plus lifestyle measures; thiazide-like diuretics are appropriate first-line agents.

Reference: 2025 AHA/ACC High Blood Pressure Guideline