A 70-year-old woman with osteoarthritis and eGFR 34 mL/min/1.73 m2 takes ibuprofen daily. Blood pressure has increased and creatinine has risen from

Question

A 70-year-old woman with osteoarthritis and eGFR 34 mL/min/1.73 m2 takes ibuprofen daily. Blood pressure has increased and creatinine has risen from baseline. She has no inflammatory arthritis. Which of the following would you recommend at the follow-up visit?

Accepted Answer

Stop NSAIDs and use safer analgesic options

Answer

Start chronic gentamicin

Answer

Add a second NSAID

Answer

Restrict fluids to 500 mL daily

Answer

Increase ibuprofen dose

Medication safety in CKD — USMLE Step 3 MCQ

A 70-year-old woman with osteoarthritis and eGFR 34 mL/min/1.73 m2 takes ibuprofen daily. Blood pressure has increased and creatinine has risen from baseline. She has no inflammatory arthritis. Which of the following would you recommend at the follow-up visit?