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Acute asthma exacerbation — USMLE Step 3 MCQ

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EasyEmergency MedicineAcute asthma exacerbationUSMLE Step 3

A 30-year-old woman with asthma has severe wheeze after viral symptoms. She speaks in short phrases. Peak expiratory flow is 35% predicted and oxygen saturation is 90%. Which of the following is the most appropriate next step in management?

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Correct answer: CGive inhaled albuterol plus ipratropium and systemic corticosteroids

Severe asthma exacerbation requires rapid bronchodilation, systemic corticosteroids, and oxygen titrated to saturation.

Reference: NAEPP Asthma Guidelines; GINA Strategy 2025