Recurrent gout — USMLE Step 3 MCQ
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Correct answer: D — Start allopurinol with flare prophylaxis and titrate to serum urate target
Explanation lettering: E = shown as A · D = shown as B · A = shown as D · B = shown as E
Recurrent flares support urate-lowering therapy, commonly allopurinol, with prophylaxis during initiation. B is insufficient alone. C increases urate. D and E do not treat gout pathophysiology.
Reference: American College of Rheumatology, Gout Guideline: https://rheumatology.org/gout-guideline