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Primary aldosteronism — USMLE Step 3 MCQ

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ModerateInternal Medicine (Chronic Management)Primary aldosteronismUSMLE Step 3

A 61-year-old man has hypertension despite lisinopril, amlodipine, and chlorthalidone. Home readings average 154/88 mm Hg. Potassium is 3.1 mEq/L. He has no edema and takes medications reliably. Which of the following is the most likely diagnosis?

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Correct answer: EPrimary aldosteronism

Resistant hypertension with hypokalemia suggests primary aldosteronism.

Reference: AHA/ACC high blood pressure guidance, https://www.ahajournals.org/doi/10.1161/HYP.0000000000000249