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Cervical cancer screening — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareCervical cancer screeningUSMLE Step 3

A 35-year-old woman with a cervix has a normal Pap test 5 years ago. She has no history of CIN2, immunosuppression, or DES exposure. She asks about screening options. Which of the following is the most appropriate screening recommendation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Perform primary high-risk HPV testing every 5 years

For ages 30 to 65, options include cytology every 3 years, primary hrHPV every 5 years, or cotesting every 5 years.

Reference: USPSTF cervical cancer screening, https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening