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Idiopathic pulmonary fibrosis — USMLE Step 3 MCQ

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HardInternal Medicine (Chronic Management)Idiopathic pulmonary fibrosisUSMLE Step 3

A 68-year-old man has progressive exertional dyspnea and dry cough for 1 year. He has bibasilar crackles and clubbing. High-resolution CT shows subpleural basilar reticulation and honeycombing. Autoimmune testing is negative. Which of the following is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Idiopathic pulmonary fibrosis

Older age, clubbing, progressive dyspnea, and usual interstitial pneumonia pattern support idiopathic pulmonary fibrosis.

Reference: Current US clinical practice standards and USMLE Step 3 content outline, https://www.usmle.org/exam-resources/step-3-materials