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Graves disease — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateInternal Medicine (Chronic Management)Graves diseaseUSMLE Step 3

A 34-year-old woman has weight loss, tremor, palpitations, and diffuse goiter. TSH is suppressed, free T4 is elevated, and thyrotropin receptor antibody is positive. She is not pregnant and has no liver disease. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Start methimazole and a beta blocker

Nonpregnant Graves hyperthyroidism is commonly treated initially with methimazole plus beta blockade for symptoms.

Reference: Current US clinical practice standards and USMLE Step 3 content outline, https://www.usmle.org/exam-resources/step-3-materials