Acute ischemic stroke — USMLE Step 3 MCQ
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Correct answer: A — Manage without platelet transfusion for aspirin reversal
The best answer is “Manage without platelet transfusion for aspirin reversal”. For spontaneous ICH in an aspirin-treated patient not requiring emergency surgery and without severe thrombocytopenia, platelet transfusion is potentially harmful and should not be used routinely. This differs from selected emergency neurosurgical circumstances. Normal platelet count and the absence of planned emergency surgery are the decisive qualifiers in this scenario.
Reference: 2022 AHA/ASA Guideline for Spontaneous Intracerebral Hemorrhage: https://professional.heart.org/en/science-news/2022-guideline-for-the-management-of-patients-with-spontaneous-intracerebral-hemorrhage/top-things-to-know