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HFpEF — USMLE Step 3 MCQ

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ModerateInternal Medicine (Chronic Management)HFpEFUSMLE Step 3

A 73-year-old woman with hypertension and diabetes has exertional dyspnea and ankle edema. Echocardiogram shows LVEF 58% and diastolic dysfunction. BNP is elevated. She improves with low-dose diuretic therapy. Which of the following would you recommend at the follow-up visit?

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Correct answer: AAdd an SGLT2 inhibitor if no contraindication

SGLT2 inhibitors reduce heart failure hospitalization in HFpEF and are recommended when appropriate.

Reference: AHA/ACC/HFSA heart failure guideline, https://www.jacc.org/doi/10.1016/j.jacc.2021.12.012