skip to main content

Opioid overdose — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

EasyEmergency MedicineOpioid overdoseUSMLE Step 3

A 31-year-old man is found unresponsive with slow respirations. Respiratory rate is 6/min, pupils are pinpoint, and oxygen saturation is 82%. Glucose is normal and there are needle marks on his arms. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Provide ventilation support and naloxone

Opioid overdose causes respiratory depression and miosis; treatment prioritizes ventilation and naloxone.

Reference: Current US clinical practice standards and USMLE Step 3 content outline, https://www.usmle.org/exam-resources/step-3-materials