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NNT — USMLE Step 3 MCQ

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ModeratePreventive Medicine, Epidemiology, BiostatisticsNNTUSMLE Step 3

A randomized trial of a smoking cessation intervention reports 12-month abstinence in 24% of the intervention group and 16% of usual care. Adverse events are similar. A clinician wants the practical effect size. Which of the following is the most likely explanation for this patient's findings?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: DThe number needed to treat is 13

Absolute benefit is 8%; NNT is 1/0.08 = 12.5, rounded up to 13.

Reference: Current US clinical practice standards and USMLE Step 3 content outline, https://www.usmle.org/exam-resources/step-3-materials