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New type 2 diabetes — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareNew type 2 diabetesUSMLE Step 3

A 48-year-old woman establishes care. BMI is 34 kg/m2 and repeat A1c is 7.8%. She has no weight loss, ketosis, cardiovascular disease, kidney disease, or medication contraindication. She is motivated to change diet and activity. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: AStart metformin with lifestyle modification

Metformin with lifestyle change is appropriate initial therapy for most nonpregnant adults with mild newly diagnosed type 2 diabetes.

Reference: ADA Standards of Care in Diabetes 2026, https://professional.diabetes.org/standards-of-care