skip to main content

Osteoporosis treatment — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

EasyAmbulatory Medicine / Primary CareOsteoporosis treatmentUSMLE Step 3

A 68-year-old woman has femoral neck T-score of -2.8 on DXA. Calcium is normal, vitamin D deficiency has been corrected, and eGFR is 78 mL/min/1.73 m2. She has no esophageal stricture or dental procedure planned. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BStart oral alendronate

A bisphosphonate is first-line pharmacologic therapy for postmenopausal osteoporosis when safe to use.

Reference: USPSTF A and B recommendations, https://www.uspreventiveservicestaskforce.org/uspstf/recommendation-topics/uspstf-a-and-b-recommendations